Furocoumarins ofDictamnus dasycarpus

Biosynthesis of Furocoumarins

The Authors have studied the biosynthesis of some furocoumarins contained in Ruta graveolens. Labeled 5,7and 7,8-dihydroxycoumarins have been administered to the herb, however practically no incorporation of radioactivity was observed in the isolated furocoumarins. Moreover, with the aim to study in a more detailed way the role of rutaretin and marmesin, trapping experiments have been performed...

Dark and photohemolysis of erythrocytes by furocoumarins.

It has been shown that various furocoumarins are able to cause dark hemolysis in red blood cells (RBC). However, this effect is evident only at relatively high furocoumarin concentrations (4.6 x 10(-4) M) - much higher than those used in photosensitization experiments or photochemotherapeutic treatments. Among the various furocoumarins examined in this study, only psoralen (Ps) and 3-carbethoxy...

Photoreactivity of Furocoumarins with Nucleic Acids

The photoreaction at 3655 Ä between skin-photosensitizing furocoumarins and DNA leads to a photo-C4-cyclo-addition reaction in which the 5 — 6 double bond of the pyrimidine bases and the 3 — 4 or the 4' —5' double bond of the furocoumarins are involved. In continuing the research in this field, the authors have investigated the photoreactions (3655 A) of psoralen, xanthotoxin (8-methoxy-psorale...

Furocoumarins in Sun Protection and Bronzing Products

Eudesmane-Type Sesquiterpene Glycosides from Dictamnus dasycarpus Turcz.

Eudesmane-type sesquiterpenes have been reported to exhibit varieties of biological activities. During the process of investigating this kind of natural product from the root bark of Dictamnus dasycarpus Turcz., 13 eudesmane-type sesquiterpene glycosides including six new isolates, named as dictameudesmnosides A₁ (1), A₂ (2), B (3), C (4), D (5), and E (6), together with seven known ones (7-13)...